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Single-cell RNA-sequencing analyses identify heterogeneity of CD8(+) T cell subpopulations and novel therapy targets in melanoma
CD8(+) T cells are crucial to establish antitumor immunity, and their high infiltration associates with favorable prognoses. However, several CD8(+) T cell subpopulations in the tumor microenvironment may play different roles in prognosis, progression, and immunotherapy. Here, we analyzed prior publ...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851490/ https://www.ncbi.nlm.nih.gov/pubmed/33575475 http://dx.doi.org/10.1016/j.omto.2020.12.003 |