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Single-cell RNA-sequencing analyses identify heterogeneity of CD8(+) T cell subpopulations and novel therapy targets in melanoma

CD8(+) T cells are crucial to establish antitumor immunity, and their high infiltration associates with favorable prognoses. However, several CD8(+) T cell subpopulations in the tumor microenvironment may play different roles in prognosis, progression, and immunotherapy. Here, we analyzed prior publ...

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Detalles Bibliográficos
Autores principales: Deng, Weiwei, Ma, Yubo, Su, Zhen, Liu, Yufang, Liang, Panpan, Huang, Chen, Liu, Xiao, Shao, Jin, Zhang, Yi, Zhang, Kai, Chen, Jian, Li, Ruoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851490/
https://www.ncbi.nlm.nih.gov/pubmed/33575475
http://dx.doi.org/10.1016/j.omto.2020.12.003