IOX-101 Reverses Drug Resistance Through Suppression of Akt/mTOR/NF-κB Signaling in Cancer Stem Cell-Like, Sphere-Forming NSCLC Cell

Drug discovery research to fight lung cancer is incessantly challenged by drug resistance. In this study, we used drug-resistant lung cancer stem like cells (A549-CS) to compare the efficacy of standard drugs like cisplatin (DDP) and gemcitabine (GEM) with a novel arylidene derivative IOX-101. A549-...

Descripción completa

Detalles Bibliográficos
Autores principales: Fayi, Majed Al, Alamri, Ahmad, Rajagopalan, Prasanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851539/
https://www.ncbi.nlm.nih.gov/pubmed/31771696
http://dx.doi.org/10.3727/096504019X15746768080428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851539/
https://www.ncbi.nlm.nih.gov/pubmed/31771696
http://dx.doi.org/10.3727/096504019X15746768080428

Ejemplares similares