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Cylindromatosis Is Required for Survival of a Subset of Melanoma Cells

The deubiquitinase cylindromatosis (CYLD) functions as a tumor suppressor inhibiting cell proliferation in many cancer types including melanoma. Here we present evidence that a proportion of melanoma cells are nonetheless addicted to CYLD for survival. The expression levels of CYLD varied widely in...

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Detalles Bibliográficos
Autores principales: La, Ting, Jin, Lei, Liu, Xiao Ying, Song, Ze Hua, Farrelly, Margaret, Feng, Yu Chen, Yan, Xu Guang, Zhang, Yuan Yuan, Thorne, Rick F., Zhang, Xu Dong, Teng, Liu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851542/
https://www.ncbi.nlm.nih.gov/pubmed/32252875
http://dx.doi.org/10.3727/096504020X15861709922491