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Epstein-Barr Virus-Encoded Latent Membrane Protein 1 and B-Cell Growth Transformation Induce Lipogenesis through Fatty Acid Synthase

Latent membrane protein 1 (LMP1) is the major transforming protein of Epstein-Barr virus (EBV) and is critical for EBV-induced B-cell transformation in vitro. Several B-cell malignancies are associated with latent LMP1-positive EBV infection, including Hodgkin’s and diffuse large B-cell lymphomas. W...

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Detalles Bibliográficos
Autores principales: Hulse, Michael, Johnson, Sarah M., Boyle, Sarah, Caruso, Lisa Beatrice, Tempera, Italo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851568/
https://www.ncbi.nlm.nih.gov/pubmed/33208446
http://dx.doi.org/10.1128/JVI.01857-20