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Genetic Polymorphism Effect on Warfarin–Rifampin Interaction: A Case Report and Review of Literature
Warfarin–rifampin interaction has been reported since the 1970s. Due to rifampin’s strong induction of CYP2C9, most cases could not attain the target international normalized ratio (INR) despite warfarin dose escalation. Genetic polymorphisms determine up to 50% of warfarin dose variability. A 38-ye...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851577/ https://www.ncbi.nlm.nih.gov/pubmed/33542643 http://dx.doi.org/10.2147/PGPM.S288918 |