Genetic Polymorphism Effect on Warfarin–Rifampin Interaction: A Case Report and Review of Literature

Warfarin–rifampin interaction has been reported since the 1970s. Due to rifampin’s strong induction of CYP2C9, most cases could not attain the target international normalized ratio (INR) despite warfarin dose escalation. Genetic polymorphisms determine up to 50% of warfarin dose variability. A 38-ye...

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Detalles Bibliográficos
Autores principales: Salem, Muhammad, Eljilany, Islam, El-Bardissy, Ahmed, Elewa, Hazem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851577/
https://www.ncbi.nlm.nih.gov/pubmed/33542643
http://dx.doi.org/10.2147/PGPM.S288918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851577/
https://www.ncbi.nlm.nih.gov/pubmed/33542643
http://dx.doi.org/10.2147/PGPM.S288918

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