Inhibition of the mevalonate pathway improves myocardial fibrosis

The mevalonate (MVA) pathway serves an important role in ventricular remodeling. Targeting the MVA pathway has protective effects against myocardial fibrosis. The present study aimed to investigate the mechanism behind these effects. Primary cultured cardiac fibroblasts from C57BL/6 mice were treate...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Huifeng, Shen, Yi, Liang, Chenyu, Wang, Haifeng, Huang, Junling, Xue, Pengcheng, Luo, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851600/
https://www.ncbi.nlm.nih.gov/pubmed/33603833
http://dx.doi.org/10.3892/etm.2021.9655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851600/
https://www.ncbi.nlm.nih.gov/pubmed/33603833
http://dx.doi.org/10.3892/etm.2021.9655

Ejemplares similares