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Inhibition of heat shock protein 90 alleviates cholestatic liver injury by decreasing IL-1β and IL-18 expression

Severe cholestatic liver injury diseases, such as obstructive jaundice and the subsequent acute obstructive cholangitis, are induced by biliary tract occlusion. Heat shock protein 90 (HSP90) inhibitors have been demonstrated to be protective for various organs. The potential of HSP90 inhibitors in t...

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Detalles Bibliográficos
Autores principales: Tong, Chenhao, Li, Jiandong, Lin, Weiguo, Cen, Wenda, Zhang, Weiguang, Zhu, Zhiyang, Lu, Baochun, Yu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851627/
https://www.ncbi.nlm.nih.gov/pubmed/33603849
http://dx.doi.org/10.3892/etm.2021.9672