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A CRISPR Interference Platform for Selective Downregulation of Gene Expression in Borrelia burgdorferi

The spirochete Borrelia burgdorferi causes Lyme disease, an increasingly prevalent infection. While previous studies have provided important insight into B. burgdorferi biology, many aspects, including basic cellular processes, remain underexplored. To help speed up the discovery process, we adapted...

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Detalles Bibliográficos
Autores principales: Takacs, Constantin N., Scott, Molly, Chang, Yunjie, Kloos, Zachary A., Irnov, Irnov, Rosa, Patricia A., Liu, Jun, Jacobs-Wagner, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851697/
https://www.ncbi.nlm.nih.gov/pubmed/33257311
http://dx.doi.org/10.1128/AEM.02519-20