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Molecular modeling and design of some β-amino alcohol grafted 1,4,5-trisubstituted 1,2,3-triazoles derivatives against chloroquine sensitive, 3D7 strain of Plasmodium falciparum

Resistance nature of Plasmodium falciparum (P. falciparum) to the most effective antimalarial drug, Artemisinin, intimidate the global goal of total eradication of malarial. In an attempt to overcome this challenge, the research was aimed at designing derivatives of β-amino alcohol grafted 1,4,5-tri...

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Detalles Bibliográficos
Autores principales: Ibrahim, Zakari Ya'u, Uzairu, Adamu, Shallangwa, Gideon Adamu, Abechi, Stephen Eyije
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851792/
https://www.ncbi.nlm.nih.gov/pubmed/33553724
http://dx.doi.org/10.1016/j.heliyon.2021.e05924