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Systems biology analysis identifies TNFRSF9 as a functional marker of tumor-infiltrating regulatory T-cell enabling clinical outcome prediction in lung cancer

Regulatory T cells (Tregs) are enriched in the tumor microenvironment and play key roles in immune evasion of cancer cells. Cell surface markers specific for tumor-infiltrating Tregs (TI-Tregs) can be effectively targeted to enhance antitumor immunity and used for stratification of immunotherapy out...

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Detalles Bibliográficos
Autores principales: Cho, Jae-Won, Son, Jimin, Ha, Sang-Jun, Lee, Insuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851794/
https://www.ncbi.nlm.nih.gov/pubmed/33598101
http://dx.doi.org/10.1016/j.csbj.2021.01.025