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NuMA interaction with chromatin is vital for proper chromosome decondensation at the mitotic exit
NuMA is an abundant long coiled-coil protein that plays a prominent role in spindle organization during mitosis. In interphase, NuMA is localized to the nucleus and hypothesized to control gene expression and chromatin organization. However, because of the prominent mitotic phenotype upon NuMA loss,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851854/ https://www.ncbi.nlm.nih.gov/pubmed/32845810 http://dx.doi.org/10.1091/mbc.E20-06-0415 |