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NuMA interaction with chromatin is vital for proper chromosome decondensation at the mitotic exit

NuMA is an abundant long coiled-coil protein that plays a prominent role in spindle organization during mitosis. In interphase, NuMA is localized to the nucleus and hypothesized to control gene expression and chromatin organization. However, because of the prominent mitotic phenotype upon NuMA loss,...

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Detalles Bibliográficos
Autores principales: Rajeevan, Ashwathi, Keshri, Riya, Kapoor, Sukriti, Kotak, Sachin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851854/
https://www.ncbi.nlm.nih.gov/pubmed/32845810
http://dx.doi.org/10.1091/mbc.E20-06-0415