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Structurally distinct endocytic pathways for B cell receptors in B lymphocytes

B lymphocytes play a critical role in adaptive immunity. On antigen binding, B cell receptors (BCR) cluster on the plasma membrane and are internalized by endocytosis. In this process, B cells capture diverse antigens in various contexts and concentrations. However, it is unclear whether the mechani...

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Detalles Bibliográficos
Autores principales: Roberts, Aleah D., Davenport, Thaddeus M., Dickey, Andrea M., Ahn, Regina, Sochacki, Kem A., Taraska, Justin W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851864/
https://www.ncbi.nlm.nih.gov/pubmed/33085561
http://dx.doi.org/10.1091/mbc.E20-08-0532