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RAC1 induces nuclear alterations through the LINC complex to enhance melanoma invasiveness

RHO GTPases are key regulators of the cytoskeletal architecture, which impact a broad range of biological processes in malignant cells including motility, invasion, and metastasis, thereby affecting tumor progression. One of the constraints during cell migration is the diameter of the pores through...

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Detalles Bibliográficos
Autores principales: Colón-Bolea, Paula, García-Gómez, Rocío, Shackleton, Sue, Crespo, Piero, Bustelo, Xosé R., Casar, Berta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851868/
https://www.ncbi.nlm.nih.gov/pubmed/33026942
http://dx.doi.org/10.1091/mbc.E20-02-0127