The prion-like domain of Fused in Sarcoma is phosphorylated by multiple kinases affecting liquid- and solid-phase transitions

Fused in Sarcoma (FUS) is a ubiquitously expressed protein that can phase-separate from nucleoplasm and cytoplasm into distinct liquid-droplet structures. It is predominantly nuclear and most of its functions are related to RNA and DNA metabolism. Excessive persistence of FUS within cytoplasmic phas...

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Detalles Bibliográficos
Autores principales: Owen, Izzy, Rhoads, Shannon, Yee, Debra, Wyne, Hala, Gery, Kevin, Hannula, Isabelle, Sundrum, Meenakshi, Shewmaker, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851872/
https://www.ncbi.nlm.nih.gov/pubmed/32877292
http://dx.doi.org/10.1091/mbc.E20-05-0290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851872/
https://www.ncbi.nlm.nih.gov/pubmed/32877292
http://dx.doi.org/10.1091/mbc.E20-05-0290

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