Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells

BACKGROUND: Shikonin (SKO) is a natural naphthoquinone derived from Chinese herbal medicine Arnebiae Radix with high development potentials due to its anti-inflammatory and anti-tumor activities. Overwhelming evidences have indicated that SKO can induce both necrosis and apoptosis in cancer cells, w...

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Detalles Bibliográficos
Autores principales: Wang, Anqi, Liu, Jiayu, Yang, Yuhan, Chen, Zhejie, Gao, Caifang, Wang, Zhanguo, Fu, Chaomei, Zou, Liang, Wang, Shengpeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851907/
https://www.ncbi.nlm.nih.gov/pubmed/33526051
http://dx.doi.org/10.1186/s13020-021-00426-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851907/
https://www.ncbi.nlm.nih.gov/pubmed/33526051
http://dx.doi.org/10.1186/s13020-021-00426-1

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