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LINC00460/DHX9/IGF2BP2 complex promotes colorectal cancer proliferation and metastasis by mediating HMGA1 mRNA stability depending on m6A modification

BACKGROUND: Increasing studies have shown that long noncoding RNAs (lncRNAs) are pivotal regulators participating in carcinogenic progression and tumor metastasis in colorectal cancer (CRC). Although lncRNA long intergenic noncoding RNA 460 (LINC00460) has been reported in CRC, the role and molecula...

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Detalles Bibliográficos
Autores principales: Hou, Pingfu, Meng, Sen, Li, Minle, Lin, Tian, Chu, Sufang, Li, Zhongwei, Zheng, Junnian, Gu, Yuming, Bai, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851923/
https://www.ncbi.nlm.nih.gov/pubmed/33526059
http://dx.doi.org/10.1186/s13046-021-01857-2