Lamin A/C deficiency enables increased myosin-II bipolar filament ensembles that promote divergent actomyosin network anomalies through self-organization

Nuclear envelope proteins influence cell cytoarchitecure by poorly understood mechanisms. Here we show that small interfering RNA–mediated silencing of lamin A/C (LMNA) promotes contrasting stress fiber assembly and disassembly in individual cells and within cell populations. We show that LMNA-defic...

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Detalles Bibliográficos
Autores principales: Wiggan, O’Neil, DeLuca, Jennifer G., Stasevich, Timothy J., Bamburg, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851964/
https://www.ncbi.nlm.nih.gov/pubmed/32816614
http://dx.doi.org/10.1091/mbc.E20-01-0017-T

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851964/
https://www.ncbi.nlm.nih.gov/pubmed/32816614
http://dx.doi.org/10.1091/mbc.E20-01-0017-T

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