Cargando…
Lamin A/C deficiency enables increased myosin-II bipolar filament ensembles that promote divergent actomyosin network anomalies through self-organization
Nuclear envelope proteins influence cell cytoarchitecure by poorly understood mechanisms. Here we show that small interfering RNA–mediated silencing of lamin A/C (LMNA) promotes contrasting stress fiber assembly and disassembly in individual cells and within cell populations. We show that LMNA-defic...
Autores principales: | Wiggan, O’Neil, DeLuca, Jennifer G., Stasevich, Timothy J., Bamburg, James R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7851964/ https://www.ncbi.nlm.nih.gov/pubmed/32816614 http://dx.doi.org/10.1091/mbc.E20-01-0017-T |
Ejemplares similares
-
Cofilin Regulates Nuclear Architecture through a Myosin-II Dependent Mechanotransduction Module
por: Wiggan, O’Neil, et al.
Publicado: (2017) -
Myosin and gelsolin cooperate in actin filament severing and actomyosin motor activity
por: Vemula, Venukumar, et al.
Publicado: (2020) -
Myosin turnover controls actomyosin contractile instability
por: Thiyagarajan, Sathish, et al.
Publicado: (2022) -
Cofilin and Actin Dynamics: Multiple Modes of Regulation and Their Impacts in Neuronal Development and Degeneration
por: Bamburg, James R., et al.
Publicado: (2021) -
Dictyostelium Myosin Bipolar Thick Filament Formation: Importance of Charge and Specific Domains of the Myosin Rod
por: Hostetter, Daniel, et al.
Publicado: (2004)