Inhibition of Kpnβ1 mediated nuclear import enhances cisplatin chemosensitivity in cervical cancer

BACKGROUND: Inhibition of nuclear import via Karyopherin beta 1 (Kpnβ1) shows potential as an anti-cancer approach. This study investigated the use of nuclear import inhibitor, INI-43, in combination with cisplatin. METHODS: Cervical cancer cells were pre-treated with INI-43 before treatment with ci...

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Detalles Bibliográficos
Autores principales: Chi, Ru-pin Alicia, van der Watt, Pauline, Wei, Wei, Birrer, Michael J., Leaner, Virna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852134/
https://www.ncbi.nlm.nih.gov/pubmed/33530952
http://dx.doi.org/10.1186/s12885-021-07819-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852134/
https://www.ncbi.nlm.nih.gov/pubmed/33530952
http://dx.doi.org/10.1186/s12885-021-07819-3

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