Alternative polyadenylation: methods, mechanism, function, and role in cancer

Occurring in over 60% of human genes, alternative polyadenylation (APA) results in numerous transcripts with differing 3’ends, thus greatly expanding the diversity of mRNAs and of proteins derived from a single gene. As a key molecular mechanism, APA is involved in various gene regulation steps incl...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Liu, Lian, Qiu, Qiongzi, Zhou, Qing, Ding, Jinwang, Lu, Yan, Liu, Pengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852185/
https://www.ncbi.nlm.nih.gov/pubmed/33526057
http://dx.doi.org/10.1186/s13046-021-01852-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852185/
https://www.ncbi.nlm.nih.gov/pubmed/33526057
http://dx.doi.org/10.1186/s13046-021-01852-7

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