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Glucosepane is associated with changes to structural and physical properties of collagen fibrils

Collagen glycation, and in particular the formation of advanced glycation end-product (AGE) crosslinks, plays a central role in the ageing process and in many of the long-term complications of diabetes. Glucosepane, the most abundant and relevant AGE crosslink, has been suggested to increase the sti...

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Detalles Bibliográficos
Autores principales: Nash, Anthony, Notou, Maria, Lopez-Clavijo, Andrea F., Bozec, Laurent, de Leeuw, Nora H., Birch, Helen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852203/
https://www.ncbi.nlm.nih.gov/pubmed/33543010
http://dx.doi.org/10.1016/j.mbplus.2019.100013