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CCN1 expression by fibroblasts is required for bleomycin-induced skin fibrosis

The microenvironment contributes to the excessive connective tissue deposition that characterizes fibrosis. Members of the CCN family of matricellular proteins are secreted by fibroblasts into the fibrotic microenvironment; however, the role of endogenous CCN1 in skin fibrosis is unknown. Mice harbo...

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Detalles Bibliográficos
Autores principales: Quesnel, Katherine, Shi-wen, Xu, Hutchenreuther, James, Xiao, Yizhi, Liu, Shangxi, Peidl, Alexander, Naskar, Deboki, Siqueira, Walter L., O'Gorman, David B., Hinz, Boris, Stratton, Richard J., Leask, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852207/
https://www.ncbi.nlm.nih.gov/pubmed/33543008
http://dx.doi.org/10.1016/j.mbplus.2019.100009