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CCN1 expression by fibroblasts is required for bleomycin-induced skin fibrosis
The microenvironment contributes to the excessive connective tissue deposition that characterizes fibrosis. Members of the CCN family of matricellular proteins are secreted by fibroblasts into the fibrotic microenvironment; however, the role of endogenous CCN1 in skin fibrosis is unknown. Mice harbo...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852207/ https://www.ncbi.nlm.nih.gov/pubmed/33543008 http://dx.doi.org/10.1016/j.mbplus.2019.100009 |