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Adipose-derived stromal cell secreted factors induce the elastogenesis cascade within 3D aortic smooth muscle cell constructs

OBJECTIVE: Elastogenesis within the medial layer of the aortic wall involves a cascade of events orchestrated primarily by smooth muscle cells, including transcription of elastin and a cadre of elastin chaperone matricellular proteins, deposition and cross-linking of tropoelastin coacervates, and ma...

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Detalles Bibliográficos
Autores principales: Ramaswamy, Aneesh K., Sides, Rachel E., Cunnane, Eoghan M., Lorentz, Katherine L., Reines, Leila M., Vorp, David A., Weinbaum, Justin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852215/
https://www.ncbi.nlm.nih.gov/pubmed/33543011
http://dx.doi.org/10.1016/j.mbplus.2019.100014