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Adipose-derived stromal cell secreted factors induce the elastogenesis cascade within 3D aortic smooth muscle cell constructs
OBJECTIVE: Elastogenesis within the medial layer of the aortic wall involves a cascade of events orchestrated primarily by smooth muscle cells, including transcription of elastin and a cadre of elastin chaperone matricellular proteins, deposition and cross-linking of tropoelastin coacervates, and ma...
Autores principales: | Ramaswamy, Aneesh K., Sides, Rachel E., Cunnane, Eoghan M., Lorentz, Katherine L., Reines, Leila M., Vorp, David A., Weinbaum, Justin S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852215/ https://www.ncbi.nlm.nih.gov/pubmed/33543011 http://dx.doi.org/10.1016/j.mbplus.2019.100014 |
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