Oligodeoxynucleotides containing unmethylated cytosine-guanine motifs are effective immunostimulants against pneumococcal meningitis in the immunocompetent and neutropenic host

BACKGROUND: Bacterial meningitis is a fatal disease with a mortality up to 30% and neurological sequelae in one fourth of survivors. Available vaccines do not fully protect against this lethal disease. Here, we report the protective effect of synthetic oligodeoxynucleotides containing unmethylated c...

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Detalles Bibliográficos
Autores principales: Ribes, S., Zacke, L., Nessler, S., Saiepour, N., Avendaño-Guzmán, E., Ballüer, M., Hanisch, U. K., Nau, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852218/
https://www.ncbi.nlm.nih.gov/pubmed/33531028
http://dx.doi.org/10.1186/s12974-021-02077-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852218/
https://www.ncbi.nlm.nih.gov/pubmed/33531028
http://dx.doi.org/10.1186/s12974-021-02077-3

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