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Development of spike receptor-binding domain nanoparticle as a vaccine candidate against SARS-CoV-2 infection in ferrets

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a causative agent of COVID-19 pandemic, enters host cells via the interaction of its Receptor-Binding Domain (RBD) of Spike protein with host Angiotensin-Converting Enzyme 2 (ACE2). Therefore, RBD is a promising vaccine target to induce p...

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Detalles Bibliográficos
Autores principales: Kim, Young-Il, Kim, Dokyun, Yu, Kwang-Min, Seo, Hogyu David, Lee, Shin-Ae, Casel, Mark Anthony B., Jang, Seung-Gyu, Kim, Stephanie, Jung, WooRam, Lai, Chih-Jen, Choi, Young Ki, Jung, Jae U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852231/
https://www.ncbi.nlm.nih.gov/pubmed/33532767
http://dx.doi.org/10.1101/2021.01.28.428743