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Magnitude and timing of the antiviral response determine SARS-CoV-2 replication early in infection

The interferon response is a potent antiviral defense mechanism, but its effectiveness depends on its timing relative to viral replication. Here, we report viral replication and host response kinetics in patients at the start of SARS-CoV-2 infection and explore the impact of these kinetics experimen...

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Detalles Bibliográficos
Autores principales: Cheemarla, Nagarjuna R., Watkins, Timothy A., Mihaylova, Valia T., Wang, Bao, Zhao, Dejian, Wang, Guilin, Landry, Marie L., Foxman, Ellen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852233/
https://www.ncbi.nlm.nih.gov/pubmed/33532783
http://dx.doi.org/10.1101/2021.01.22.21249812