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Mechanism of Viral Glycoprotein Targeting by Membrane-associated-RING-CH Proteins

An emerging class of cellular inhibitory proteins has been identified that targets viral glycoproteins. These include the membrane-associated RING-CH (MARCH) family of E3 ubiquitin ligases that, among other functions, downregulate cell-surface proteins involved in adaptive immunity. The RING-CH doma...

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Detalles Bibliográficos
Autores principales: Lun, Cheng Man, Waheed, Abdul A., Majadly, Alhlam, Powell, Nicole, Freed, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852266/
https://www.ncbi.nlm.nih.gov/pubmed/33532773
http://dx.doi.org/10.1101/2021.01.25.428025