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Synthetic nanobody–SARS-CoV-2 receptor-binding domain structures identify distinct epitopes

The worldwide spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) demands unprecedented attention. We report four X-ray crystal structures of three synthetic nanobodies (sybodies) (Sb16, Sb45 and Sb68) bind to the receptor-binding domain (RBD) of SARS-CoV-2: binary complexes of Sb...

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Detalles Bibliográficos
Autores principales: Ahmad, Javeed, Jiang, Jiansheng, Boyd, Lisa F., Natarajan, Kannan, Margulies, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852268/
https://www.ncbi.nlm.nih.gov/pubmed/33532775
http://dx.doi.org/10.1101/2021.01.27.428466