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Factors affecting serum phenobarbital concentration changes in pediatric patients receiving elixir and powder formulations

BACKGROUND: Phenobarbital (PB) is commonly used as elixir and powder formulations in pediatric care. Its dose adjustment is performed based on individual drug concentration monitoring. Few studies have comprehensively analyzed the variation factors for serum PB concentration. In this study, we retro...

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Detalles Bibliográficos
Autores principales: Shiraishi, Chihiro, Matsuda, Hiroko, Ogura, Toru, Iwamoto, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852295/
https://www.ncbi.nlm.nih.gov/pubmed/33526089
http://dx.doi.org/10.1186/s40780-021-00190-2