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Proteomic fingerprints of damage in extracellular matrix assemblies

In contrast to the dynamic intracellular environment, structural extracellular matrix (ECM) proteins with half-lives measured in decades, are susceptible to accumulating damage. Whilst conventional approaches such as histology, immunohistochemistry and mass spectrometry are able to identify age- and...

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Detalles Bibliográficos
Autores principales: Eckersley, Alexander, Ozols, Matiss, O'Cualain, Ronan, Keevill, Emma-Jayne, Foster, April, Pilkington, Suzanne, Knight, David, Griffiths, Christopher E.M., Watson, Rachel E.B., Sherratt, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852314/
https://www.ncbi.nlm.nih.gov/pubmed/33543016
http://dx.doi.org/10.1016/j.mbplus.2020.100027