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Calreticulin is important for the development of renal fibrosis and dysfunction in diabetic nephropathy

Previously, our lab showed that the endoplasmic reticulum (ER) and calcium regulatory protein, calreticulin (CRT), is important for collagen transcription, secretion, and assembly into the extracellular matrix (ECM) and that ER CRT is critical for TGF-β stimulation of type I collagen transcription t...

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Detalles Bibliográficos
Autores principales: Lu, Ailing, Pallero, Manuel A., Owusu, Benjamin Y., Borovjagin, Anton V., Lei, Weiqi, Sanders, Paul W., Murphy-Ullrich, Joanne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852315/
https://www.ncbi.nlm.nih.gov/pubmed/33543033
http://dx.doi.org/10.1016/j.mbplus.2020.100034