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Quantitative proteomic profiling of extracellular matrix and site-specific collagen post-translational modifications in an in vitro model of lung fibrosis

Lung fibrosis is characterized by excessive deposition of extracellular matrix (ECM), in particular collagens, by fibroblasts in the interstitium. Transforming growth factor-β1 (TGF-β1) alters the expression of many extracellular matrix (ECM) components produced by fibroblasts, but such changes in E...

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Detalles Bibliográficos
Autores principales: Merl-Pham, Juliane, Basak, Trayambak, Knüppel, Larissa, Ramanujam, Deepak, Athanason, Mark, Behr, Jürgen, Engelhardt, Stefan, Eickelberg, Oliver, Hauck, Stefanie M., Vanacore, Roberto, Staab-Weijnitz, Claudia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852317/
https://www.ncbi.nlm.nih.gov/pubmed/33543004
http://dx.doi.org/10.1016/j.mbplus.2019.04.002