Serglycin activates pro-tumorigenic signaling and controls glioblastoma cell stemness, differentiation and invasive potential

Despite the functional role of serglycin as an intracellular proteoglycan, a variety of malignant cells depends on its expression and constitutive secretion to advance their aggressive behavior. Serglycin arose to be a biomarker for glioblastoma, which is the deadliest and most treatment-resistant f...

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Detalles Bibliográficos
Autores principales: Manou, Dimitra, Bouris, Panagiotis, Kletsas, Dimitris, Götte, Martin, Greve, Burkhard, Moustakas, Aristidis, Karamanos, Nikos K., Theocharis, Achilleas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852318/
https://www.ncbi.nlm.nih.gov/pubmed/33543029
http://dx.doi.org/10.1016/j.mbplus.2020.100033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852318/
https://www.ncbi.nlm.nih.gov/pubmed/33543029
http://dx.doi.org/10.1016/j.mbplus.2020.100033

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