Cargando…
Serglycin activates pro-tumorigenic signaling and controls glioblastoma cell stemness, differentiation and invasive potential
Despite the functional role of serglycin as an intracellular proteoglycan, a variety of malignant cells depends on its expression and constitutive secretion to advance their aggressive behavior. Serglycin arose to be a biomarker for glioblastoma, which is the deadliest and most treatment-resistant f...
Autores principales: | Manou, Dimitra, Bouris, Panagiotis, Kletsas, Dimitris, Götte, Martin, Greve, Burkhard, Moustakas, Aristidis, Karamanos, Nikos K., Theocharis, Achilleas D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852318/ https://www.ncbi.nlm.nih.gov/pubmed/33543029 http://dx.doi.org/10.1016/j.mbplus.2020.100033 |
Ejemplares similares
-
Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines
por: Korpetinou, Angeliki, et al.
Publicado: (2015) -
Serglycin: At the Crossroad of Inflammation and Malignancy
por: Korpetinou, Angeliki, et al.
Publicado: (2014) -
Serglycin Is Implicated in the Promotion of Aggressive Phenotype of Breast Cancer Cells
por: Korpetinou, Angeliki, et al.
Publicado: (2013) -
IGF-IR cooperates with ERα to inhibit breast cancer cell aggressiveness by regulating the expression and localisation of ECM molecules
por: Afratis, Nikolaos A., et al.
Publicado: (2017) -
Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression
por: Roy, Ananya, et al.
Publicado: (2017)