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Allysine modifications perturb tropoelastin structure and mobility on a local and global scale

Elastin provides elastic tissues with resilience through stretch and recoil cycles, and is primarily made of its extensively cross-linked monomer, tropoelastin. Here, we leverage the recently published full atomistic model of tropoelastin to assess how allysine modifications, which are essential to...

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Detalles Bibliográficos
Autores principales: Ozsvar, Jazmin, Tarakanova, Anna, Wang, Richard, Buehler, Markus J., Weiss, Anthony S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852328/
https://www.ncbi.nlm.nih.gov/pubmed/33543005
http://dx.doi.org/10.1016/j.mbplus.2019.03.001