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Alterations in ECM signature underscore multiple sub-phenotypes of intervertebral disc degeneration

The intervertebral disc is a specialized connective tissue critical for absorption of mechanical loads and providing flexibility to the spinal column. The disc ECM is complex and plays a vital role in imparting tissue its biomechanical function. The central NP is primarily composed of large aggregat...

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Detalles Bibliográficos
Autores principales: Ohnishi, Takashi, Novais, Emanuel J., Risbud, Makarand V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852332/
https://www.ncbi.nlm.nih.gov/pubmed/33543030
http://dx.doi.org/10.1016/j.mbplus.2020.100036