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Alterations in ECM signature underscore multiple sub-phenotypes of intervertebral disc degeneration
The intervertebral disc is a specialized connective tissue critical for absorption of mechanical loads and providing flexibility to the spinal column. The disc ECM is complex and plays a vital role in imparting tissue its biomechanical function. The central NP is primarily composed of large aggregat...
Autores principales: | Ohnishi, Takashi, Novais, Emanuel J., Risbud, Makarand V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852332/ https://www.ncbi.nlm.nih.gov/pubmed/33543030 http://dx.doi.org/10.1016/j.mbplus.2020.100036 |
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