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Clonal evolution in liver cancer at single-cell and single-variant resolution

Genetic heterogeneity of tumor is closely related to its clonal evolution, phenotypic diversity and treatment resistance, and such heterogeneity has only been characterized at single-cell sub-chromosomal scale in liver cancer. Here we reconstructed the single-variant resolution clonal evolution in h...

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Detalles Bibliográficos
Autores principales: Su, Xianbin, Zhao, Linan, Shi, Yi, Zhang, Rui, Long, Qi, Bai, Shihao, Luo, Qing, Lin, Yingxin, Zou, Xin, Ghazanfar, Shila, Tao, Kun, Yang, Guoliang, Wang, Lan, He, Kun-Yan, Cui, Xiaofang, He, Jian, Wu, Jiao-Xiang, Han, Bo, Yan, Bin, Deng, Biao, Wang, Na, Li, Xiaolin, Yang, Pengyi, Hou, Shangwei, Sun, Jielin, Yang, Jean Y. H., Chen, Jinhong, Han, Ze-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852352/
https://www.ncbi.nlm.nih.gov/pubmed/33531041
http://dx.doi.org/10.1186/s13045-021-01036-y