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Inhibition of neutral sphingomyelinase 2 promotes remyelination

Myelination requires a highly organized synthesis of multiple lipid species that regulate myelin curvature and compaction. For reasons that are not understood, central nervous system remyelinated axons often have thin myelin sheaths with a disorganized structure susceptible to secondary demyelinatio...

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Detalles Bibliográficos
Autores principales: Yoo, Seung-Wan, Agarwal, Amit, Smith, Matthew D., Khuder, Saja S., Baxi, Emily G., Thomas, Ajit G., Rojas, Camilo, Moniruzzaman, Mohammed, Slusher, Barbara S., Bergles, Dwight E., Calabresi, Peter A., Haughey, Norman J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852391/
https://www.ncbi.nlm.nih.gov/pubmed/33008902
http://dx.doi.org/10.1126/sciadv.aba5210