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Autophagy as a therapeutic target in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is characterised by early metastasis and resistance to anti-cancer therapy, leading to an overall poor prognosis. Despite continued research efforts, no targeted therapy has yet shown meaningful efficacy in PDAC; mutations in the oncogene KRAS and the tumour s...

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Detalles Bibliográficos
Autores principales: Piffoux, Max, Eriau, Erwan, Cassier, Philippe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852577/
https://www.ncbi.nlm.nih.gov/pubmed/32929194
http://dx.doi.org/10.1038/s41416-020-01039-5