Phosphorylation by Aurora B kinase regulates caspase-2 activity and function

Mitotic catastrophe (MC) is an important oncosuppressive mechanism that serves to eliminate cells that become polyploid or aneuploid due to aberrant mitosis. Previous studies have demonstrated that the activation and catalytic function of caspase-2 are key steps in MC to trigger apoptosis and/or cel...

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Detalles Bibliográficos
Autores principales: Lim, Yoon, De Bellis, Dylan, Sandow, Jarrod J., Capalbo, Luisa, D’Avino, Pier Paolo, Murphy, James M., Webb, Andrew I., Dorstyn, Loretta, Kumar, Sharad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852673/
https://www.ncbi.nlm.nih.gov/pubmed/32811973
http://dx.doi.org/10.1038/s41418-020-00604-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852673/
https://www.ncbi.nlm.nih.gov/pubmed/32811973
http://dx.doi.org/10.1038/s41418-020-00604-y

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