Survival of patients with deficient mismatch repair metastatic colorectal cancer in the pre-immunotherapy era

BACKGROUND: Metastatic colorectal cancer patients with deficient mismatch repair (dMMR mCRC) benefit from immunotherapy. Interpretation of the single-arm immunotherapy trials is complicated by insignificant survival data during systemic non-immunotherapy. We present survival data on a large, compreh...

Descripción completa

Detalles Bibliográficos
Autores principales: Wensink, G. Emerens, Elferink, Marloes A. G., May, Anne M., Mol, Linda, Hamers, Patricia A. H., Bakker, Sandra D., Creemers, Geert-Jan, de Groot, Jan Willem B., de Klerk, Gerty J., Haberkorn, Brigitte C. M., Haringhuizen, Annebeth W., Hoekstra, Ronald, Hunting, J. Cornelis B., Kerver, Emile D., Mathijssen-van Stein, Danielle, Polée, Marco B., Pruijt, Johannes F. M., Quarles van Ufford-Mannesse, Patricia, Radema, Sandra, Rietbroek, Ronald C., Simkens, Lieke H. J., Tanis, Bea C., ten Bokkel Huinink, Daan, Tjin-A-Ton, Manuel L. R., Tromp-van Driel, Cathrien S., Troost, Monique M., van de Wouw, Agnes J., van den Berkmortel, Franchette W. P. J., van der Pas, Anke J. M., van der Velden, Ankie M. T., van Dijk, Marjan A., van Dodewaard-de Jong, Joyce M., van Druten, Edith B., van Voorthuizen, Theo, Jan Veldhuis, Gerrit, Verheul, Henk M. W., Vestjens, Hanneke J. H. M. J., Vincent, Jeroen, Kranenburg, Onno W., Punt, Cornelis J. A., Vink, Geraldine R., Roodhart, Jeanine M. L., Koopman, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852682/
https://www.ncbi.nlm.nih.gov/pubmed/33046804
http://dx.doi.org/10.1038/s41416-020-01076-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852682/
https://www.ncbi.nlm.nih.gov/pubmed/33046804
http://dx.doi.org/10.1038/s41416-020-01076-0

Ejemplares similares