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G3BP1 interacts with YWHAZ to regulate chemoresistance and predict adjuvant chemotherapy benefit in gastric cancer

BACKGROUND: A large proportion of gastric cancer patients are susceptible to chemoresistance, while the underlying mechanism remains obscure. Stress granules (SGs) play a self-defence role for tumour cells in inhibiting chemotherapy-induced apoptosis. As an SG assembly effector, G3BP1 (Ras-GTPase-ac...

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Detalles Bibliográficos
Autores principales: Zhao, Junjie, Fu, Xuhong, Chen, Hao, Min, Lingqiang, Sun, Jie, Yin, Jingyi, Guo, Jianping, Li, Haojie, Tang, Zhaoqing, Ruan, Yuanyuan, Wang, Xuefei, Sun, Yihong, Huang, Liyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852868/
https://www.ncbi.nlm.nih.gov/pubmed/32989225
http://dx.doi.org/10.1038/s41416-020-01067-1