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Inbred lab mice are not isogenic: genetic variation within inbred strains used to infer the mutation rate per nucleotide site
For over a century, inbred mice have been used in many areas of genetics research to gain insight into the genetic variation underlying traits of interest. The generalizability of any genetic research study in inbred mice is dependent upon all individual mice being genetically identical, which in tu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852876/ https://www.ncbi.nlm.nih.gov/pubmed/32868871 http://dx.doi.org/10.1038/s41437-020-00361-1 |