Droplet-digital PCR reveals frequent mutations in TERT promoter region in breast fibroadenomas and phyllodes tumours, irrespective of the presence of MED12 mutations

BACKGROUND: Breast fibroadenoma (FA) and phyllodes tumour (PT) often have variations of gene mediator complex subunit 12 (MED12) and mutations in the telomerase reverse transcriptase promoter region (TERTp). TERTp mutation is usually tested by Sanger sequencing. In this study, we compared Sanger seq...

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Detalles Bibliográficos
Autores principales: Otsuji, Kazutaka, Sasaki, Takeshi, Tanabe, Masahiko, Seto, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852881/
https://www.ncbi.nlm.nih.gov/pubmed/33046803
http://dx.doi.org/10.1038/s41416-020-01109-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852881/
https://www.ncbi.nlm.nih.gov/pubmed/33046803
http://dx.doi.org/10.1038/s41416-020-01109-8

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