STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment

BACKGROUND: The degree of immune infiltration in tumors, especially CD8(+) T cells, greatly impacts patient disease course and response to interventional immunotherapy. Enhancement of tumor infiltrating lymphocyte (TIL) is a critical element of efficacious therapy and one that may be achieved via ad...

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Detalles Bibliográficos
Autores principales: Chelvanambi, Manoj, Fecek, Ronald J, Taylor, Jennifer L, Storkus, Walter J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852948/
https://www.ncbi.nlm.nih.gov/pubmed/33526609
http://dx.doi.org/10.1136/jitc-2020-001906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852948/
https://www.ncbi.nlm.nih.gov/pubmed/33526609
http://dx.doi.org/10.1136/jitc-2020-001906

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