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Long-term safety and efficacy of sirukumab for patients with rheumatoid arthritis who previously received sirukumab in randomised controlled trials (SIRROUND-LTE)

OBJECTIVE: Interleukin (IL)-6 is a pleiotropic cytokine involved in the pathophysiology of rheumatoid arthritis (RA). Sirukumab is a human monoclonal antibody that binds to IL-6 with high affinity and specificity. METHODS: This long-term extension (LTE) study of the SIRROUND-D and SIRROUND-T studies...

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Detalles Bibliográficos
Autores principales: Aletaha, Daniel, Bingham, Clifton O, Karpouzas, George Athanasios, Takeuchi, Tsutomu, Thorne, Carter, Bili, Androniki, Agarwal, Prasheen, Hsu, Benjamin, Rao, Ravi, Brown, Kurt, Tanaka, Yoshiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7852950/
https://www.ncbi.nlm.nih.gov/pubmed/33526709
http://dx.doi.org/10.1136/rmdopen-2020-001465