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Yolk sac-derived Pdcd11-positive cells modulate zebrafish microglia differentiation through the NF-κB-Tgfβ1 pathway

Microglia are the primary immune cells in the central nervous system, which plays a vital role in neuron development and neurodegenerative diseases. Microglial precursors in peripheral hematopoietic tissues colonize the central nervous system during early embryogenesis. However, how intrinsic and ex...

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Detalles Bibliográficos
Autores principales: Yang, Ruimeng, Zhan, Ming, Guo, Miaomiao, Yuan, Hao, Wang, Yiqin, Zhang, Yiyue, Zhang, Wenqing, Chen, Saijuan, de The, Hugues, Chen, Zhu, Zhou, Jun, Zhu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853042/
https://www.ncbi.nlm.nih.gov/pubmed/32709934
http://dx.doi.org/10.1038/s41418-020-0591-3