Clinically and biologically relevant subgroups of Wilms tumour defined by genomic and epigenomic analyses

BACKGROUND: Although cure rates for Wilms tumours (WT) are high, many patients receive therapy with attendant long-term complications. Our goal was to stratify WT using genome-wide analyses to identify candidate molecular features for patients who would benefit from a reduction in therapy. METHODS:...

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Detalles Bibliográficos
Autores principales: Brzezinski, Jack, Choufani, Sanaa, Romao, Rodrigo, Shuman, Cheryl, Chen, Haiying, Cunanan, Joanna, Bagli, Darius, Grant, Ronald, Lorenzo, Armando, Weksberg, Rosanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853092/
https://www.ncbi.nlm.nih.gov/pubmed/33012783
http://dx.doi.org/10.1038/s41416-020-01102-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7853092/
https://www.ncbi.nlm.nih.gov/pubmed/33012783
http://dx.doi.org/10.1038/s41416-020-01102-1

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